Immune checkpoint inhibitors (ICI) are the Womens Shirts standard of care for various malignancies and have been associated with a wide spectrum of complications that are phenotypically akin to primary autoimmune diseases.While the literature on these toxicities is growing, there is a paucity of data regarding ICI-associated scleroderma which can c
The Pegylated lipids in lipid nanoparticle (LNPs) vaccines have been found to cause acute hypersensitivity reactions in recipients, and generate anti-LNPs immunity after repeated Godzilla administration, thereby reducing vaccine effectiveness.To overcome these challenges, we developed a new type of LNPs vaccine (SAPC-LNPs) which was co-modified wit
Charles Darwin posited that secondary sexual characteristics result from Womens Shirts competition to attract mates.In male songbirds, specialized vocalizations represent secondary sexual characteristics of particular importance because females prefer songs at specific frequencies, amplitudes, and duration.For birds living in human-dominated landsc
The goal of the present study was to investigate the role of thigmotaxis (the tendency to remain close to vertical surfaces) in rat exploratory behavior in an open-field.Thigmotaxis was investigated in a parametric way, using 24 experimentally adult naive male Wistar rats (210-230 g).Exploratory behavior was studied in an open-field (N = 12) in 5-m